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cheap iphone Cases In other words, VSI's market capitalization has shed $740 million worth of value (assuming 25 million shares x $29.53). Similar to GNC Holdings (NYSE:GNC), albeit to a much lesser extent, VSI leveraged up its balance sheet to buy back stock, as its December 31, 2015, share count was 29 million, compared to 24.2 million as of January 2018.(Source: Google Finance)Moving along, take a peek at the colorful charts I put together. These charts tell the story.cheap iphone Cases
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iphone x cases My only gripe with an acquisition would be the dilution of Ionis's ASO therapies in the milieu of chemical drugs which have an incredibly high clinical trial failure rate (greater than 90%!).Potential Risks for Ionis There are a few potential headwinds to consider:1) Ionis's primary income stream comes from Spinraza, which has recently caused the stock to trade lower due to the slow ramp in Spinraza sales. However, as more insurers provide coverage and administration sites are expanded, the majority of SMA patients should be on therapy.2) In the coming years, Spinraza could face competition from AAV based gene therapy from AveXis (NASDAQ:AVXS). While AveXis's results were definitely strong, the company will almost certainly have issues filling a placebo controlled trial with Spinraza on the market.iphone x cases
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