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Polymorphisms (normal variations) in particular genes have been linked with an increased risk of severe dengue complications. Examples include the genes coding for the proteins known as TNF, mannan binding lectin,[13] CTLA4, TGF,[28] DC SIGN, PLCE1, and particular forms of human leukocyte antigen from gene variations of HLA B.[23][31] A common genetic abnormality, especially in Africans, known as glucose 6 phosphate dehydrogenase deficiency, appears to increase the risk.[43] Polymorphisms in the genes for the vitamin D receptor and FcR seem to offer protection against severe disease in secondary dengue infection.[31]When a mosquito carrying dengue virus bites a person, the virus enters the skin together with the mosquito's saliva. It binds to and enters white blood cells, and reproduces inside the cells while they move throughout the body.

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iPhone Cases
iPhone Cases
iPhone Cases
iPhone Cases
iPhone Cases