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Paul Estrem, our CFO, will then provide an overview of our financial results and outlook for 2018. Then Dan will conclude with closing comments. Also available during the Q will be Mike McGuire, our Head of Commercial, who recently joined us from The Medicines Company; Sue Cammarata, our Chief Medical Officer; and Erin Duffy, our Chief Scientific Officer.With that, I'll turn the call over to Dan.Thanks Lisa.
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